- PERIPHERAL BLOOD KARYOTYPING
- BONE MARROW & LEUKEMIC BLOOD CHROMOSOME ANALYSIS
PERIPHERAL BLOOD KARYOTYPING
Chromosome analysis (karyotyping) is the microscopic evaluation of metaphase chromosomes for numerical and structural abnormalities associated with disease. An expert cytogenetic technologist analyzes the banded chromosomes at a microscope. Digital images of representative cells are captured and the chromosomes are arranged in a standard format known as a karyogram. Peripheral blood is the most common specimen type referred for analysis.
Normal Male Karyotype (46,XY)
BONE MARROW & LEUKEMIC BLOOD CHROMOSOME ANALYSIS
Bone marrow and leukemic blood samples that contain spontaneously dividing cells usually are cultured short-term without mitogens. Some specimens with B-cell conditions are stimulated with mitogens. Chromosome analysis of the dividing cells is useful in the diagnosis and classification of hematological malignancies
Impression: Translocation(8;21) is seen in AML M2 mostly, also rarely in M1 or M4 and treatment related leukemia t-AML. Complete remission in most cases, but relapse is frequent. Median survival is about 1.5 years in adults.
REPORT TURN AROUND TIME
- Peripheral Blood - 10 Working Days
- Bone Marrow - 10 Working Days